Prepare the Beef Mixture:
Preheat oven to 350°F (175°C).
In a mixing bowl, combine ground beef with Worcestershire sauce, garlic powder, onion powder, salt, and pepper.
Mix gently—do not overwork the beef.
Bake the Beef Layer:
Press the seasoned beef evenly into a 9x13-inch baking dish, all the way to the edges.
Bake uncovered for 15–20 minutes, or until fully cooked (internal temp of 160°F/71°C).
Carefully drain any excess grease and set aside.
Assemble the Sliders:
Slice slider buns horizontally (keep tops and bottoms connected).
Place the bottom halves in a clean 9x13-inch dish or on a baking tray.
Lay the cooked beef layer over the buns.
Top with cheese slices and any desired toppings.
Add Bun Tops and Bake Again:
Place the bun tops over the sliders.
In a small bowl, mix melted butter with garlic powder and a pinch of salt.
Brush the butter mixture generously over the tops of the buns.
Return to the oven and bake for 10–15 minutes, until cheese is melted and tops are golden.